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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(Ins2-Cd274)2Mdos
transgene insertion 2, H Michael Dosch
MGI:3701452
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
tg1
 		Tg(Ins2-Cd274)2Mdos/? NOD/ShiLt-Tg(Ins2-Cd274)2Mdos MGI:3701454


Genotype
MGI:3701454
tg1
Allelic
Composition		 Tg(Ins2-Cd274)2Mdos/?
Genetic
Background		 NOD/ShiLt-Tg(Ins2-Cd274)2Mdos
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(Ins2-Cd274)2Mdos mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
increased susceptibility to autoimmune diabetes ( J:118934 )
• non-obese diabetic (NOD) mice with this transgene exhibit acceleration of the diabetes phenotype




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory