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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Unc79Lwt
lightweight
MGI:3701691
Summary 4 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Unc79Lwt/Unc79Lwt B6.D2-Unc79Lwt MGI:4822556
hm2
 		Unc79Lwt/Unc79Lwt involves: C57BL/6J * DBA/2J MGI:3702108
ht3
 		Unc79Lwt/Unc79+ B6.D2-Unc79Lwt MGI:4822557
ht4
 		Unc79Lwt/Unc79+ involves: C57BL/6J * DBA/2J MGI:3702109


Genotype
MGI:4822556
hm1
Allelic
Composition		 Unc79Lwt/Unc79Lwt
Genetic
Background		 B6.D2-Unc79Lwt
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Unc79Lwt mutation (0 available); any Unc79 mutation (126 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging




Genotype
MGI:3702108
hm2
Allelic
Composition		 Unc79Lwt/Unc79Lwt
Genetic
Background		 involves: C57BL/6J * DBA/2J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Unc79Lwt mutation (0 available); any Unc79 mutation (126 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
increased locomotor activity ( J:118059 )
• increased spontaneous locomotor activity




Genotype
MGI:4822557
ht3
Allelic
Composition		 Unc79Lwt/Unc79+
Genetic
Background		 B6.D2-Unc79Lwt
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Unc79Lwt mutation (0 available); any Unc79 mutation (126 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
alcohol preference ( J:163308 )
• a higher preference for ethanol
enhanced behavioral response to alcohol ( J:163308 )
• an increase in sensitivity to the acute sedative effects of ethanol, loss of righting reflex test
impaired behavioral response to anesthetic ( J:163308 )
• resistance to isoflurane-induced anesthesia relative to wild-type littermates
increased fluid intake ( J:163308 )
• an increase in fluid consumption
increased alcohol consumption ( J:163308 )
• mice consume more ethanol
abnormal saccharin consumption ( J:163308 )
• an increase in the consumption of saccharin relative to wild-type
saccharin preference ( J:163308 )
• an increase in saccharin preference
hyperactivity ( J:163308 )
• modestly hyperactive

growth/size/body
decreased body weight ( J:163308 )
• weigh less than the wild-type
decreased body length ( J:163308 )
• mice are shorter in length

adipose tissue
decreased total body fat amount ( J:163308 )
• accumulate less fat




Genotype
MGI:3702109
ht4
Allelic
Composition		 Unc79Lwt/Unc79+
Genetic
Background		 involves: C57BL/6J * DBA/2J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Unc79Lwt mutation (0 available); any Unc79 mutation (126 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
increased locomotor activity ( J:118059 )
• increased spontaneous locomotor activity




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory