Phenotypes associated with this allele

• Allele Symbol: Tg(TG-TSHR)51.9Smcl
• Allele Name: transgene insertion 51.9, Sandra M McLachlan
• Allele ID: MGI:3701769
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
tg1	Tg(TG-TSHR)51.9Smcl/?	involves: BALB/c * C57BL/6	MGI:5140210

Genotype
MGI:5140210

tg1

• Allelic Composition: Tg(TG-TSHR)51.9Smcl/?
• Genetic Background: involves: BALB/c * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

immune system phenotype ( J:118100 )

N • mice do not produce antibodies to the thyroid receptor in response to low dose immunization with A-subunit adenovirus

N • high dose administration of adenovirus produces some antibody response in some transgenic animals

N • T cells do not respond to challenge with purified A-subunit protein

N • mice have normal thyroid architecture and normal levels of thyroxine (T4)