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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(Igk-Lta/Ltb)10Cys
transgene insertion 10, Jason G Cyster
MGI:3702620
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
tg1
 		Tg(Igk-Lta/Ltb)10Cys/0 involves: C57BL/6J * DBA/2J MGI:3702637


Genotype
MGI:3702637
tg1
Allelic
Composition		 Tg(Igk-Lta/Ltb)10Cys/0
Genetic
Background		 involves: C57BL/6J * DBA/2J
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♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
abnormal B cell morphology ( J:73100 )
• transgenic Lta is expressed on blood B cells; levels of lymphotoxin beta receptor immunoglobulin staining on blood B cells is similar to staining level on wild-type splenic B cells
• phenotype is almost identical to Tg(Igk-Lta/Ltb)4Cys-hemizygous mice

immune system
abnormal B cell morphology ( J:73100 )
• transgenic Lta is expressed on blood B cells; levels of lymphotoxin beta receptor immunoglobulin staining on blood B cells is similar to staining level on wild-type splenic B cells
• phenotype is almost identical to Tg(Igk-Lta/Ltb)4Cys-hemizygous mice




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory