Phenotypes associated with this allele

• Allele Symbol: Cybrd1^tm1Nca
• Allele Name: targeted mutation 1, Nancy C Andrews
• Allele ID: MGI:3702743
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Cybrd1^tm1Nca/Cybrd1^tm1Nca	involves: 129S4/SvJae * 129S6/SvEvTac	MGI:3703786

Genotype
MGI:3703786

hm1

• Allelic Composition: Cybrd1^tm1Nca/Cybrd1^tm1Nca
• Genetic Background: involves: 129S4/SvJae * 129S6/SvEvTac

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

decreased liver iron level ( J:119528 )

• on an iron defficient diet, liver iron content relative to liver and body weight is significantly decreased

• however, on a normal chow diet no significant differences in iron levels are detected in any tissue and mice are not anemic

liver/biliary system

increased liver weight ( J:119528 )

• increase in liver weight relative to body weight in mice on an iron deficient diet

• however, absolute liver and body weights are not significantly different

decreased liver iron level ( J:119528 )

• on an iron defficient diet, liver iron content relative to liver and body weight is significantly decreased

• however, on a normal chow diet no significant differences in iron levels are detected in any tissue and mice are not anemic

growth/size/body

increased liver weight ( J:119528 )

• increase in liver weight relative to body weight in mice on an iron deficient diet

• however, absolute liver and body weights are not significantly different