Phenotypes associated with this allele

• Allele Symbol: Slc14a2^tm1Suc
• Allele Name: targeted mutation 1, Shinichi Uchida
• Allele ID: MGI:3705080
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Slc14a2^tm1Suc/Slc14a2^tm1Suc	involves: 129S2/SvPas * C57BL/6J	MGI:3706699

Genotype
MGI:3706699

hm1

• Allelic Composition: Slc14a2^tm1Suc/Slc14a2^tm1Suc
• Genetic Background: involves: 129S2/SvPas * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

reproductive system

reproductive system phenotype ( J:119860 )

N • homozygous crosses yield the same number of offsping as wild-type crosses

renal/urinary system

decreased urine osmolality ( J:119860 )

• reduced maximal urine osmolarity in mice fed a low protein diet and dehydrated for 36 hours

• however, mice show given free access to food showed no difference in plasma urea, sodium, and chloride concentration or daily urine output, or daily urine output and osmolarity after a 36 hour period of water deprivation

abnormal renal transport ( J:119860 )

• reduced papillary osmolarity and medullary urea concentration in the renal inner medulla when fed a low protein diet and dehydrated for 36 hours

homeostasis/metabolism

decreased urine osmolality ( J:119860 )

• reduced maximal urine osmolarity in mice fed a low protein diet and dehydrated for 36 hours

• however, mice show given free access to food showed no difference in plasma urea, sodium, and chloride concentration or daily urine output, or daily urine output and osmolarity after a 36 hour period of water deprivation