Phenotypes associated with this allele

• Allele Symbol: Rnf212^repro57
• Allele Name: reproductive mutant 10, JAX Reproductive Mutagenesis Program
• Allele ID: MGI:3708256
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Rnf212^repro57/Rnf212^repro57	B6;C3Fe-Rnf212^repro57/J	MGI:3709004

Genotype
MGI:3709004

hm1

• Allelic Composition: Rnf212^repro57/Rnf212^repro57
• Genetic Background: B6;C3Fe-Rnf212^repro57/J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

reproductive system

abnormal germ cell morphology ( J:92463 )

• some germ cells appear apoptotic

azoospermia ( J:92463 )

♂ • no sperm are recovered

arrest of male meiosis ( J:92463 )

♂ • arrest of germ cells during late pachytene stage of meiotic prophase

decreased seminal vesicle weight ( J:92463 )

♂ • low seminal vesicle weight

decreased testis weight ( J:92463 )

♂ • very low testis weight

male infertility ( J:92463 )

♂

endocrine/exocrine glands

decreased seminal vesicle weight ( J:92463 )

♂ • low seminal vesicle weight

decreased testis weight ( J:92463 )

♂ • very low testis weight

cellular

abnormal germ cell morphology ( J:92463 )

• some germ cells appear apoptotic

azoospermia ( J:92463 )

♂ • no sperm are recovered

arrest of male meiosis ( J:92463 )

♂ • arrest of germ cells during late pachytene stage of meiotic prophase