Phenotypes associated with this allele

• Allele Symbol: Adgrv1^rueda
• Allele Name: rueda
• Allele ID: MGI:3708270
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Adgrv1^rueda/Adgrv1^rueda	involves: C57BL/6J	MGI:3709034

Genotype
MGI:3709034

hm1

• Allelic Composition: Adgrv1^rueda/Adgrv1^rueda
• Genetic Background: involves: C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

decreased startle reflex ( J:119820 )

• low auditory startle response

hearing/vestibular/ear

abnormal orientation of outer hair cell stereociliary bundles ( J:119820 )

• with of hair bundles in outer hair cell is irregular

• bundles are organized asymmetrically with one side of the bundle being longer than other

• kinocilia in hair cells are shifted to ectopic positions and the polarization of the hair bundles is perturbed

increased or absent threshold for auditory brainstem response ( J:119820 )

• auditory threshold of 90 dB, indicating that lines are severely hearing impaired in 3-weeks old and 2 month old animals

nervous system

abnormal orientation of outer hair cell stereociliary bundles ( J:119820 )

• with of hair bundles in outer hair cell is irregular

• bundles are organized asymmetrically with one side of the bundle being longer than other

• kinocilia in hair cells are shifted to ectopic positions and the polarization of the hair bundles is perturbed