About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Otofpga
pachanga
MGI:3708344
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Otofpga/Otofpga involves: C57BL/6J MGI:3709036


Genotype
MGI:3709036
hm1
Allelic
Composition		 Otofpga/Otofpga
Genetic
Background		 involves: C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Otofpga mutation (0 available); any Otof mutation (110 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
decreased startle reflex ( J:119820 )
• low auditory startle response

hearing/vestibular/ear
abnormal cochlear hair cell stereociliary bundle morphology ( J:119820 )
• hair bundles appeared slightly distorted under light microscopy
• hair bundles are split at times
increased or absent threshold for auditory brainstem response ( J:119820 )
• auditory threshold of more than 90 dB, indicating that lines are severely hearing impaired in 3-weeks old and 2 month old animals

nervous system
abnormal cochlear hair cell stereociliary bundle morphology ( J:119820 )
• hair bundles appeared slightly distorted under light microscopy
• hair bundles are split at times




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory