All Phenotypes Il17rd<Gt(KST223)Byg> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Il17rd^{Gt(KST223)Byg}
gene trap KST223, BayGenomics
MGI:3709909

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Il17rd^{Gt(KST223)Byg}/Il17rd^{Gt(KST223)Byg}	B6.129P2-Il17rd^{Gt(KST223)Byg}	MGI:3711338
ht2	Il17rd^{Gt(KST223)Byg}/Il17rd⁺	B6.129P2-Il17rd^{Gt(KST223)Byg}	MGI:3711339

Allelic Composition	Il17rd^{Gt(KST223)Byg}/Il17rd^{Gt(KST223)Byg}
Genetic Background	B6.129P2-Il17rd^{Gt(KST223)Byg}

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Il17rd^{Gt(KST223)Byg} mutation (0 available); any Il17rd mutation (85 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

abnormal cochlear VIII nucleus morphology ( J:121107 )

• severe morphological defects bilaterally in one mouse in which the anterior ventral cochlear nucleus is disorganized and does not form a discrete nucleus and an outgrowth of the cerebellum covers the lateral surface of the AVCN

abnormal cerebellum morphology ( J:121107 )

• an outgrowth of the cerebellum covers the lateral surface of the AVCN in one mouse

hearing/vestibular/ear

increased or absent threshold for auditory brainstem response ( J:121107 )

• poor response to suprathreshold stimuli in which 4 of 8 mice have late wave thresholds at greater than 50dB in both ears and 2 of 8 had increased thresholds in one ear

• however, click stimuli and pure tone stimulation have normal thresholds and outer hair cells are normal

Allelic Composition	Il17rd^{Gt(KST223)Byg}/Il17rd⁺
Genetic Background	B6.129P2-Il17rd^{Gt(KST223)Byg}