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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(Myh6-Ccnd3)1Ljf
transgene insertion 1, Loren J Field
MGI:3710483
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
tg1
 		Tg(Myh6-Ccnd3)1Ljf/0 involves: C3HeB/FeJ * DBA/2J MGI:3710488


Genotype
MGI:3710488
tg1
Allelic
Composition		 Tg(Myh6-Ccnd3)1Ljf/0
Genetic
Background		 involves: C3HeB/FeJ * DBA/2J
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♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
increased heart weight ( J:104622 )
• increase in the heart weight to body weight ratio
abnormal myocardial fiber physiology ( J:104622 )
• cardiomyocyte DNA synthesis is detected in hearts, unlike in controls
• myocardial injury (isoproterenol-induced hypertrophy) reduces the ventricular cardiomyocyte DNA synthesis that is observed in mutants

growth/size/body
increased heart weight ( J:104622 )
• increase in the heart weight to body weight ratio




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory