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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Rbbp6tm1Xya
targeted mutation 1, Xiao Yang
MGI:3711066
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Rbbp6tm1Xya/Rbbp6tm1Xya involves: 129S6/SvEvTac MGI:3711894
cx2
 		Rbbp6tm1Xya/Rbbp6tm1Xya
Trp53tm1Brd/Trp53tm1Brd 		involves: 129S6/SvEvTac * 129S7/SvEvBrd MGI:3711895


Genotype
MGI:3711894
hm1
Allelic
Composition		 Rbbp6tm1Xya/Rbbp6tm1Xya
Genetic
Background		 involves: 129S6/SvEvTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rbbp6tm1Xya mutation (0 available); any Rbbp6 mutation (57 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging

embryo

cellular

growth/size/body
embryonic growth retardation ( J:121586 )
decreased embryo size ( J:121586 )




Genotype
MGI:3711895
cx2
Allelic
Composition		 Rbbp6tm1Xya/Rbbp6tm1Xya
Trp53tm1Brd/Trp53tm1Brd
Genetic
Background		 involves: 129S6/SvEvTac * 129S7/SvEvBrd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rbbp6tm1Xya mutation (0 available); any Rbbp6 mutation (57 available)
Trp53tm1Brd mutation (5 available); any Trp53 mutation (240 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality during organogenesis, incomplete penetrance ( J:121586 )
• just over half of embryos survive past E11.5

embryo
embryo phenotype ( J:121586 )
N
• unlike Rbbp6tm1Xya homozygotes, mice form anterior-posterior with a head, trunk and tail region




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory