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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tmem158tm1Srn
targeted mutation 1, Manuel Serrano
MGI:3711170
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Tmem158tm1Srn/Tmem158tm1Srn involves: 129S1/Sv * 129X1/SvJ * C57BL/6 MGI:3711656


Genotype
MGI:3711656
hm1
Allelic
Composition		 Tmem158tm1Srn/Tmem158tm1Srn
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tmem158tm1Srn mutation (0 available); any Tmem158 mutation (14 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
neoplasm
neoplasm ( J:121067 )
N
• homozygous mice do not show altered susceptibility to cancer development in models of chemical carcinogenesis; papillomas in mutants are larger (but not significantly so) compared to those seen in wild-type
• fibrosarcomas generated in another model of chemical carcinogenesis occur with same latency and have same incidence as controls




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory