Analysis Tools
homeostasis/metabolism
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• glucose infusion and glucose disposal rates are about 40% higher
• mice do not develop high fat diet-induced defects in glucose and insulin homeostasis
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• while plasma insulin levels increases after consuming high fat chow these levels decrease quicker than in wild-type mice
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• regardless of diet
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• mice only exhibit a 2-fold increased while wild-type mice fed a high fat diet exhibit an 11-fold increase
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adipose tissue
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• adipocyte size is greater when mice are fed a normal diet
• however, there is no difference in white adipose tissue mass and there is no subsequent increase in adipocyte size when mice are fed a high fat diet
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• less macrophage infiltrate into white adipose tissue than are observed in wild-type mice on a high fat diet as examined by marker expression (MCP-1 and IKK-beta)
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hematopoietic system
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• regardless of diet
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• regardless of diet
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• regardless of diet
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immune system
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• regardless of diet
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• regardless of diet
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• regardless of diet
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