Phenotypes associated with this allele

• Allele Symbol: Nrp2^{Gt(pMS-1)1Hmy}
• Allele Name: gene trap 1, Heather M Young
• Allele ID: MGI:3712239
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Nrp2^Gt(pMS-1)1Hmy/Nrp2^Gt(pMS-1)1Hmy	B6.129S1-Nrp2^Gt(pMS-1)1Hmy	MGI:3712899

Genotype
MGI:3712899

hm1

• Allelic Composition: Nrp2^{Gt(pMS-1)1Hmy}/Nrp2^{Gt(pMS-1)1Hmy}
• Genetic Background: B6.129S1-Nrp2^{Gt(pMS-1)1Hmy}

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

perinatal lethality, incomplete penetrance ( J:121340 )

• increased perinatal lethality is observed compared to wild-type

growth/size/body

decreased body size ( J:121340 )

• overall body size is reduced compared to wild-type

nervous system

nervous system phenotype ( J:121340 )

N • no change in timing of colonization of gut by sacral neural crest-derived cells is detected

abnormal innervation ( J:121340 )

• beta-gal staining and antineurofilament immunohistochemistry show that homozygous embryos essentially phenocopy previously published targeted and gene-trapped mutations of the Nrp2 locus