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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ppm1btm1.1Tamu
targeted mutation 1.1, Shinri Tamura
MGI:3712852
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Ppm1btm1.1Tamu/Ppm1btm1.1Tamu involves: C57BL/6 MGI:3713230


Genotype
MGI:3713230
hm1
Allelic
Composition		 Ppm1btm1.1Tamu/Ppm1btm1.1Tamu
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ppm1btm1.1Tamu mutation (1 available); any Ppm1b mutation (38 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality before implantation, complete penetrance ( J:121900 )
• most conceptuses die between the two-cell and eight-cell stages; no homozygous embryos are found between E7.5 and 13.5, and reduced numbers are found in litters from E1.5 to E3.5

embryo
abnormal embryonic tissue morphology ( J:121900 )
• majority of homozygous embryos identified from E1.5 to E3.5 show abnormal morphology




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory