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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Irav1DBA/2J
DBA/2J
MGI:3713729
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Irav1DBA/2J/Irav1DBA/2J involves: C57BL/6J * DBA/2J MGI:3713805
ht2
 		Irav1C57BL/J/Irav1DBA/2J involves: C57BL/6J * DBA/2J MGI:3713806


Genotype
MGI:3713805
hm1
Allelic
Composition		 Irav1DBA/2J/Irav1DBA/2J
Genetic
Background		 involves: C57BL/6J * DBA/2J
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal cell-mediated immunity ( J:122129 )
• increased cytotoxic T-cell response to adenovirus challenge
abnormal cytokine secretion ( J:122129 )
• increased TNF-alpha, IL-6, and IFN-gamma response to adenovirus challenge




Genotype
MGI:3713806
ht2
Allelic
Composition		 Irav1C57BL/J/Irav1DBA/2J
Genetic
Background		 involves: C57BL/6J * DBA/2J
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal cell-mediated immunity ( J:122129 )
• increased cytotoxic T-cell response to adenovirus challenge
abnormal cytokine secretion ( J:122129 )
• increased TNF-alpha, IL-6, and IFN-gamma response to adenovirus challenge




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory