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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ffar1tm1Lex
targeted mutation 1, Lexicon Genetics
MGI:3713759
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Ffar1tm1Lex/Ffar1tm1Lex involves: 129 * C57BL/6 MGI:3713765
hm2
 		Ffar1tm1Lex/Ffar1tm1Lex involves: C57BL/6 * C57BL/6J MGI:5510319


Genotype
MGI:3713765
hm1
Allelic
Composition		 Ffar1tm1Lex/Ffar1tm1Lex
Genetic
Background		 involves: 129 * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ffar1tm1Lex mutation (1 available); any Ffar1 mutation (18 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
endocrine/exocrine glands
decreased insulin secretion ( J:122092 )
• in response to intralipid plus heparin or palmitate

homeostasis/metabolism
decreased insulin secretion ( J:122092 )
• in response to intralipid plus heparin or palmitate




Genotype
MGI:5510319
hm2
Allelic
Composition		 Ffar1tm1Lex/Ffar1tm1Lex
Genetic
Background		 involves: C57BL/6 * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ffar1tm1Lex mutation (1 available); any Ffar1 mutation (18 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
endocrine/exocrine glands
abnormal glucagon secretion ( J:200805 )
• absence of corn oil stimulated glucagon secretion

homeostasis/metabolism
abnormal glucagon secretion ( J:200805 )
• absence of corn oil stimulated glucagon secretion
increased circulating glucose level ( J:200805 )
• in mice fed corn oil




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory