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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Zfp423Gt(XB409)Byg
gene trap XB409, BayGenomics
MGI:3714339
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Zfp423Gt(XB409)Byg/Zfp423Gt(XB409)Byg involves: 129P2/OlaHsd * C57BL/6 MGI:4879987


Genotype
MGI:4879987
hm1
Allelic
Composition
Zfp423Gt(XB409)Byg/Zfp423Gt(XB409)Byg
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Zfp423Gt(XB409)Byg mutation (0 available); any Zfp423 mutation (274 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• two (from 31 litters) survived to 3 weeks
• die within one day of birth (J:122275)
• die within 1 day of birth except two (from 31 litters) survive to 3 weeks (J:122606)

growth/size/body
• smaller than littermates

nervous system
• smaller cerebellar plate at the hindbrain
• enlarged interventricular foramen that connects the lateral ventricles with the third ventricle in the forebrain at E15.5
• form a gap in the ventral midline area at the forebrain
• enlarged fourth ventricle at the hindbrain
• smaller medulla oblongata at the hindbrain
• reduced septum in the forebrain at E15.5
• enlarged lateral ventricles in the forebrain at E15.5

behavior/neurological
• severe ataxia in mice survive to 3 weeks
• unable to maintain their balance and show poorly coordinated movement





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory