Phenotypes associated with this allele

• Allele Symbol: Tg(ACTA1-Arntl)1Jt
• Allele Name: transgene insertion 1, Joseph S Takahashi
• Allele ID: MGI:3714751
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cx1	Bmal1^tm1Bra/Bmal1^tm1Bra Tg(ACTA1-Arntl)1Jt/0	involves: 129/Sv * C57BL/6J * CD-1	MGI:3714769

Genotype
MGI:3714769

cx1

• Allelic Composition: Bmal1^tm1Bra/Bmal1^tm1Bra; Tg(ACTA1-Arntl)1Jt/0
• Genetic Background: involves: 129/Sv * C57BL/6J * CD-1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

mortality/aging ( J:116189 )

N • 100% of rescued mice survive to end of experiment (>10 months) compared to 29% of Arntl-null mice

behavior/neurological

abnormal circadian behavior ( J:116189 )

• mice with muscle rescue do not show circadian rhythmicity of activity, but level of activity is not significantly different from wild-type mice

growth/size/body

decreased body size ( J:116189 )

• at 4 to 6 months of age, rescued mice body weight is lower than wild-type, but not really significantly

skeleton

calcified calcaneal tendon ( J:116189 )

• significant calcaneal tendon calcification is observed in rescued mice similar to Arntl-null animals

muscle

calcified calcaneal tendon ( J:116189 )

• significant calcaneal tendon calcification is observed in rescued mice similar to Arntl-null animals