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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Del(14)3Mom
deletion, Chr 14, Peter Mombaerts 3
MGI:3714752
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Del(14)3Mom/Del(14)3Mom involves: 129P2/OlaHsd * C57BL/6J MGI:3715979
ht2
Del(14)3Mom/+ (C57BL/6J x 129P2/OlaHsd)F1 MGI:3716106


Genotype
MGI:3715979
hm1
Allelic
Composition
Del(14)3Mom/Del(14)3Mom
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Del(14)3Mom mutation (1 available); any Del(14)3Mom mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
taste/olfaction
N
• Despite the absence of the H element, homozygotes express most olfactory receptor genes and olfactory receptor-specific coalescence of axons into glomeruli is normal
• abolished expression of Olfr1507, Olfr1508, and Olfr1509, and a tapered reduction in expression of some of the more distal Chromosome 14 olfactory receptors

nervous system
• abolished expression of Olfr1507, Olfr1508, and Olfr1509, and a tapered reduction in expression of some of the more distal Chromosome 14 olfactory receptors

craniofacial
• abolished expression of Olfr1507, Olfr1508, and Olfr1509, and a tapered reduction in expression of some of the more distal Chromosome 14 olfactory receptors

respiratory system
• abolished expression of Olfr1507, Olfr1508, and Olfr1509, and a tapered reduction in expression of some of the more distal Chromosome 14 olfactory receptors

growth/size/body
• abolished expression of Olfr1507, Olfr1508, and Olfr1509, and a tapered reduction in expression of some of the more distal Chromosome 14 olfactory receptors




Genotype
MGI:3716106
ht2
Allelic
Composition
Del(14)3Mom/+
Genetic
Background
(C57BL/6J x 129P2/OlaHsd)F1
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Del(14)3Mom mutation (1 available); any Del(14)3Mom mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
taste/olfaction
• loss or diminished expression of a subset of olfactory receptors that are on the same chromosome as the deletion, with less impact on olfactory receptor genes with increased chromosomal distance from the deletion and no impact on expression of olfactory receptors expressed in trans

nervous system
• loss or diminished expression of a subset of olfactory receptors that are on the same chromosome as the deletion, with less impact on olfactory receptor genes with increased chromosomal distance from the deletion and no impact on expression of olfactory receptors expressed in trans

craniofacial
• loss or diminished expression of a subset of olfactory receptors that are on the same chromosome as the deletion, with less impact on olfactory receptor genes with increased chromosomal distance from the deletion and no impact on expression of olfactory receptors expressed in trans

respiratory system
• loss or diminished expression of a subset of olfactory receptors that are on the same chromosome as the deletion, with less impact on olfactory receptor genes with increased chromosomal distance from the deletion and no impact on expression of olfactory receptors expressed in trans

growth/size/body
• loss or diminished expression of a subset of olfactory receptors that are on the same chromosome as the deletion, with less impact on olfactory receptor genes with increased chromosomal distance from the deletion and no impact on expression of olfactory receptors expressed in trans





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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory