All Phenotypes Itgb1<tm4Ref> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Itgb1^tm4Ref
targeted mutation 4, Reinhard Fassler
MGI:3714996

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Itgb1^tm4Ref/Itgb1^tm4Ref Tg(Ins2-cre)1Heed/? Tg(RIP1-Tag)2Dh/?	involves: C57BL/6 * C57BL/6J * CBA * DBA/2J	MGI:3715016

Allelic Composition	Itgb1^tm4Ref/Itgb1^tm4Ref Tg(Ins2-cre)1Heed/? Tg(RIP1-Tag)2Dh/?
Genetic Background	involves: C57BL/6 * C57BL/6J * CBA * DBA/2J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Itgb1^tm4Ref mutation (0 available); any Itgb1 mutation (60 available)
Tg(Ins2-cre)1Heed mutation (0 available)
Tg(RIP1-Tag)2Dh mutation (2 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

neoplasm

abnormal tumor susceptibility ( J:122649 )

• similar to Itgb1^tm1Ref Tg(Ins2-cre)1Heed Tg(RIP1-Tag)2Dh, mice exhibit reduced tumor burden and increased tumor cell embolization in the lymphatics

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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