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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Shisa2tm1Sia
targeted mutation 1, Shinichi Aizawa
MGI:3715222
Summary 4 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Shisa2tm1Sia/Shisa2tm1Sia involves: C57BL/6 * CBA MGI:3715231
cx2
Lefty1tm1Hmd/Lefty1tm1Hmd
Shisa2tm1Sia/Shisa2tm1Sia
involves: 129P2/OlaHsd * C57BL/6 * CBA MGI:3718480
cx3
Lefty2tm1Hmd/Lefty2tm1Hmd
Shisa2tm1Sia/Shisa2tm1Sia
involves: 129P2/OlaHsd * C57BL/6 * CBA MGI:3718481
cx4
Cer1tm1Belo/Cer1tm1Belo
Shisa2tm1Sia/Shisa2tm1Sia
involves: 129X1/SvJ * C57BL/6 * CBA MGI:3718479


Genotype
MGI:3715231
hm1
Allelic
Composition
Shisa2tm1Sia/Shisa2tm1Sia
Genetic
Background
involves: C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Shisa2tm1Sia mutation (0 available); any Shisa2 mutation (10 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• half of mice die within the first month

growth/size/body
• two thirds of mice

nervous system
• dying dwarf mice exhibit abnormal thalamus with an expansion of the space between the cerebrum and thalamus




Genotype
MGI:3718480
cx2
Allelic
Composition
Lefty1tm1Hmd/Lefty1tm1Hmd
Shisa2tm1Sia/Shisa2tm1Sia
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lefty1tm1Hmd mutation (1 available); any Lefty1 mutation (41 available)
Shisa2tm1Sia mutation (0 available); any Shisa2 mutation (10 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
N
• no defects in anterior neuroectoderm development are detected




Genotype
MGI:3718481
cx3
Allelic
Composition
Lefty2tm1Hmd/Lefty2tm1Hmd
Shisa2tm1Sia/Shisa2tm1Sia
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lefty2tm1Hmd mutation (1 available); any Lefty2 mutation (14 available)
Shisa2tm1Sia mutation (0 available); any Shisa2 mutation (10 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
N
• no defects in anterior neuroectoderm development are detected




Genotype
MGI:3718479
cx4
Allelic
Composition
Cer1tm1Belo/Cer1tm1Belo
Shisa2tm1Sia/Shisa2tm1Sia
Genetic
Background
involves: 129X1/SvJ * C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cer1tm1Belo mutation (0 available); any Cer1 mutation (11 available)
Shisa2tm1Sia mutation (0 available); any Shisa2 mutation (10 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
N
• no defects in anterior neuroectoderm development are detected





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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory