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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Bmp4tm3.2Blh
targeted mutation 3.2, Brigid L Hogan
MGI:3715255
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Bmp4tm3.2Blh/Bmp4+
Grem1tm1Azun/Grem1tm1Azun
Tg(Hoxb7-EGFP)33Cos/? 		involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * BALB/cJ * C57BL/6 * CBA MGI:3715256
cx2
 		Bmp4tm3.2Blh/Bmp4tm3.2Blh
Grem1tm1Azun/Grem1tm1Azun
Tg(Hoxb7-EGFP)33Cos/? 		involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * BALB/cJ * C57BL/6 * CBA MGI:3715257


Genotype
MGI:3715256
cx1
Allelic
Composition		 Bmp4tm3.2Blh/Bmp4+
Grem1tm1Azun/Grem1tm1Azun
Tg(Hoxb7-EGFP)33Cos/?
Genetic
Background		 involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * BALB/cJ * C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Bmp4tm3.2Blh mutation (0 available); any Bmp4 mutation (23 available)
Grem1tm1Azun mutation (1 available); any Grem1 mutation (19 available)
Tg(Hoxb7-EGFP)33Cos mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
renal/urinary system
renal/urinary system phenotype ( J:122530 )
N
• kidneys develop and function normally unlike in Grem1tm1Azun homozygotes




Genotype
MGI:3715257
cx2
Allelic
Composition		 Bmp4tm3.2Blh/Bmp4tm3.2Blh
Grem1tm1Azun/Grem1tm1Azun
Tg(Hoxb7-EGFP)33Cos/?
Genetic
Background		 involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * BALB/cJ * C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Bmp4tm3.2Blh mutation (0 available); any Bmp4 mutation (23 available)
Grem1tm1Azun mutation (1 available); any Grem1 mutation (19 available)
Tg(Hoxb7-EGFP)33Cos mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
prenatal lethality ( J:122530 )
• mice exhibit early lethality similar to Bmp4 deficient mice




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory