Phenotypes associated with this allele

• Allele Symbol: Mesp2^{tm13(cre/Esr1*)Ysa}
• Allele Name: targeted mutation 13, Yumiko Saga
• Allele ID: MGI:3715268
• Summary: 3 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Mesp2^tm13(cre/Esr1*)Ysa/Mesp2^tm13(cre/Esr1*)Ysa	involves: C57BL/6 * SJL	MGI:3715272
ht2	Mesp2^tm13(cre/Esr1*)Ysa/Mesp2^+	involves: C57BL/6J	MGI:5431509
ht3	Mesp2^tm13(cre/Esr1*)Ysa/Mesp2^+	Not Specified	MGI:5431508

Genotype
MGI:3715272

hm1

• Allelic Composition: Mesp2^{tm13(cre/Esr1*)Ysa}/Mesp2^{tm13(cre/Esr1*)Ysa}
• Genetic Background: involves: C57BL/6 * SJL

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

embryo

abnormal somite development ( J:122532 )

• somite development defects are similar to those seen in Mesp2^tm4Ysa homozygotes

• however, some signs of a somite boundary can be seen at E11.5

Genotype
MGI:5431509

ht2

• Allelic Composition: Mesp2^{tm13(cre/Esr1*)Ysa}/Mesp2⁺
• Genetic Background: involves: C57BL/6J

skeleton

abnormal vertebrae morphology ( J:186213 )

• following exposure to mild hypoxia, mice exhibit increased rate and severity of vertebrae defects compared with wild-type mice

Genotype
MGI:5431508

ht3

• Allelic Composition: Mesp2^{tm13(cre/Esr1*)Ysa}/Mesp2⁺
• Genetic Background: Not Specified

skeleton

abnormal vertebrae morphology ( J:186213 )

• in few mice at E14.5