behavior/neurological
N |
• ataxic gait seen in Grm1tm1Stl homozygotes is rescued by the active transgene
|
• following treatment with doxycycline begun at P24, mice fall off a rotating rod immediately and after several trials the average retention time is less than in wild-type mice at 41 days post treatment
|
• following treatment with doxycycline begun at P24, mice have abnormal gaits and steps with different degrees of severity at 37 days post treatment
|