About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Syt5tm2Sud
targeted mutation 2, Thomas C Sudhof
MGI:3715453
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Syt5tm2Sud/Syt5tm2Sud involves: 129S1/Sv * 129X1/SvJ MGI:3715457
cn2
 		Syt5tm2Sud/Syt5tm2Sud involves: 129S1/Sv * 129X1/SvJ MGI:3715455


Genotype
MGI:3715457
hm1
Allelic
Composition		 Syt5tm2Sud/Syt5tm2Sud
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Syt5tm2Sud mutation (0 available); any Syt5 mutation (15 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
nervous system phenotype ( J:122459 )
N
• inhibitions of postsynaptic currents is normal




Genotype
MGI:3715455
cn2
Allelic
Composition		 Syt5tm2Sud/Syt5tm2Sud
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Syt5tm2Sud mutation (0 available); any Syt5 mutation (15 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal inhibitory postsynaptic currents ( J:122459 )
• following infection with a lentivirus expression cre, inhibitions of postsynaptic currents (IPSCs) are severely impaired (63% decreased in synaptic amplitude)




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory