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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Itpr1m1Asb
mutation 1, Andrew B Singleton
MGI:3715928
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Itpr1m1Asb/Itpr1m1Asb involves: 129X1/SvJ * C57BL/6 MGI:3716755
ht2
 		Itpr1m1Asb/Itpr1opt involves: 129X1/SvJ * C57BL/6 * C57BLKS MGI:3716754


Genotype
MGI:3716755
hm1
Allelic
Composition		 Itpr1m1Asb/Itpr1m1Asb
Genetic
Background		 involves: 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Itpr1m1Asb mutation (1 available); any Itpr1 mutation (184 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
premature death ( J:122793 )
• without weaning, affected mice survive about 4 weeks after onset of symptoms

behavior/neurological
abnormal involuntary movement ( J:122793 )
• mice display paroxysmal movement disorder, often induced by touch
• abnormal movements occur predominantly below cervical level, and appear progressive
• phenotype presents at postnatal day 14




Genotype
MGI:3716754
ht2
Allelic
Composition		 Itpr1m1Asb/Itpr1opt
Genetic
Background		 involves: 129X1/SvJ * C57BL/6 * C57BLKS
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Itpr1m1Asb mutation (1 available); any Itpr1 mutation (184 available)
Itpr1opt mutation (2 available); any Itpr1 mutation (184 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
premature death ( J:122793 )
• phenotype is stated to be identical to that of Iptr1m1Asb or Iptr1opt homozygotes; however no data is presented

behavior/neurological




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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory