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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(AMELX-LRAP)9Gibs
transgene insertion 9, Carolyn Gibson
MGI:3716151
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Amelxtm1Kul/Amelxtm1Kul
Tg(AMELX-LRAP)9Gibs/0 		involves: 129S1/Sv * 129X1/SvJ MGI:5086218
tg2
 		Tg(AMELX-LRAP)9Gibs/0 Not Specified MGI:5086217


Genotype
MGI:5086218
cx1
Allelic
Composition		 Amelxtm1Kul/Amelxtm1Kul
Tg(AMELX-LRAP)9Gibs/0
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Amelxtm1Kul mutation (2 available); any Amelx mutation (26 available)
Tg(AMELX-LRAP)9Gibs mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
craniofacial
abnormal enamel morphology ( J:122916 )
• molar enamel surface has a rough appearance
abnormal enamel rod pattern ( J:122916 )
• hypoplastic enamel lacks normal prism structure
reduced enamel thickness ( J:122916 )
• enamel thickness is 10-20 um in contrast to 100 um observed in wild-type mice

growth/size/body
abnormal enamel morphology ( J:122916 )
• molar enamel surface has a rough appearance
abnormal enamel rod pattern ( J:122916 )
• hypoplastic enamel lacks normal prism structure
reduced enamel thickness ( J:122916 )
• enamel thickness is 10-20 um in contrast to 100 um observed in wild-type mice

skeleton
abnormal enamel morphology ( J:122916 )
• molar enamel surface has a rough appearance
abnormal enamel rod pattern ( J:122916 )
• hypoplastic enamel lacks normal prism structure
reduced enamel thickness ( J:122916 )
• enamel thickness is 10-20 um in contrast to 100 um observed in wild-type mice




Genotype
MGI:5086217
tg2
Allelic
Composition		 Tg(AMELX-LRAP)9Gibs/0
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(AMELX-LRAP)9Gibs mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
craniofacial
abnormal molar morphology ( J:122916 )
• molars have a white, opaque appearance
abnormal enamel morphology ( J:122916 )
• enamel surface of molars and incisors has a cobbled appearance
• enamel thickness and prism structure is similar to wild-type

growth/size/body
abnormal molar morphology ( J:122916 )
• molars have a white, opaque appearance
abnormal enamel morphology ( J:122916 )
• enamel surface of molars and incisors has a cobbled appearance
• enamel thickness and prism structure is similar to wild-type

skeleton
abnormal molar morphology ( J:122916 )
• molars have a white, opaque appearance
abnormal enamel morphology ( J:122916 )
• enamel surface of molars and incisors has a cobbled appearance
• enamel thickness and prism structure is similar to wild-type




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Send questions and comments to User Support. 		last database update
06/12/2024
MGI 6.13 		The Jackson Laboratory