Analysis Tools
immune system
| N |
• mice are viable and fertile, and show no clinical phenotype in terms of autoimmune or spontaneous inflammatory disease; mice show normal levels and activation status of peripheral lymphoid and myeloid cells
• mice show no altered susceptibility compared to wild-type mice for endotoxic shock, experimental colitis, or bacterial infection by Listeria monocytogenes
• no significant effect in the negative regulation of Nfkb (NF-kappa B) or other proinflammatory signaling pathways is observed
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