reproductive system
infertility
(
J:108786
)
nervous system
• mice exhibit significantly longer latency, slower rise time and decreased excitatory postsynaptic currents
• when integrated over 100ms action potential induced excitatory postsynaptic currents are reduced
|
• at rest mice miniature excitatory postsynaptic current (mEPSC) frequency is potentiated almost five-fold that of wild-type mice
• following an action potential mini frequency is 2-fold higher than in wild-type mice
• frequency of mEPSC is increased
|
• miniature endplate potential in the absence or presence of extracellular calcium is several fold higher than in wild-type mice
|
behavior/neurological
• mice are severely uncoordinated
|
growth/size/body