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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Cacna1atm1(CACNA1A)Ttan
targeted mutation 1, Tsutomu Tanabe
MGI:3718032
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Cacna1atm1(CACNA1A)Ttan/Cacna1atm1(CACNA1A)Ttan involves: 129S4/SvJae MGI:3718373
ht2
Cacna1atm1(CACNA1A)Ttan/Cacna1a+ involves: 129S4/SvJae MGI:3718377


Genotype
MGI:3718373
hm1
Allelic
Composition
Cacna1atm1(CACNA1A)Ttan/Cacna1atm1(CACNA1A)Ttan
Genetic
Background
involves: 129S4/SvJae
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cacna1atm1(CACNA1A)Ttan mutation (0 available); any Cacna1a mutation (118 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• mice die around 3 weeks after birth

behavior/neurological
• severe

muscle




Genotype
MGI:3718377
ht2
Allelic
Composition
Cacna1atm1(CACNA1A)Ttan/Cacna1a+
Genetic
Background
involves: 129S4/SvJae
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cacna1atm1(CACNA1A)Ttan mutation (0 available); any Cacna1a mutation (118 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• at 6 and 12 months of age, mice exhibit a shortened latency to call compared to wild-type mice
• however, at 6 and 9 months of age, mice exhibit longer retention time compared to wild-type mice and other measures of coordination are normal





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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory