limbs/digits/tail
• at P14, mice exhibit various distal limb and paw defects
• at 6 months, mice exhibit upper limb defects and fail to develop distal paw structures
|
• defects are first visible at E12.5
• at 6 months, mice fail to develop distal paw structures and instead possess three rudimentary digit structures
|
• paws are malrotated
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• mice lack the calcaneus
|
• at 6 month, mice have fused radius and ulna
|
• at 6 month, mice have fused radius and ulna
|
short tibia
(
J:123068
)
skeleton
• mice lack the calcaneus
|
• at 6 month, mice have fused radius and ulna
|
• at 6 month, mice have fused radius and ulna
|
short tibia
(
J:123068
)