Phenotypes associated with this allele

• Allele Symbol: hlb349A
• Allele Name: heart, lung and blood, 349A
• Allele ID: MGI:3718207
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	hlb349A/hlb349A	involves: 129S1/SvImJ * C57BL/6J	MGI:3718213

Genotype
MGI:3718213

hm1

• Allelic Composition: hlb349A/hlb349A
• Genetic Background: involves: 129S1/SvImJ * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

adipose tissue

increased percent body fat/body weight ( J:82961 )

• after consuming an atherogenic diet for 3 weeks, a 12 week-old homozygous mutant mouse had a percent body fat of 22.38; female mutants become more obese than males on this regimen

growth/size/body

obese ( J:82961 )

• 12 week-old homozygous mutants fed an atherogenic diet for 3 weeks become obese, one animal weighing 30.71 g and having a percent body fat of 22.38; females are more severely affected than are males

increased susceptibility to diet-induced obesity ( J:82961 )

• the weight gain of 12 week-old homozygous mutant mice during 3 weeks on an atherogenic diet is greater than that of normal controls; the difference is greater for female than for male mice

homeostasis/metabolism

increased susceptibility to diet-induced obesity ( J:82961 )

• the weight gain of 12 week-old homozygous mutant mice during 3 weeks on an atherogenic diet is greater than that of normal controls; the difference is greater for female than for male mice