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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Slc26a5tm2Jnz
targeted mutation 2, Jian Zuo
MGI:3719391
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Slc26a5tm2Jnz/Slc26a5tm2Jnz involves: 129S6/SvEvTac * FVB/N MGI:3720494


Genotype
MGI:3720494
hm1
Allelic
Composition		 Slc26a5tm2Jnz/Slc26a5tm2Jnz
Genetic
Background		 involves: 129S6/SvEvTac * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Slc26a5tm2Jnz mutation (0 available); any Slc26a5 mutation (58 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hearing/vestibular/ear
abnormal cochlear outer hair cell electromotility ( J:123299 )
• the voltage at highest gain is shifted from wild-type mice to nulls by 70.6 mV in the hyperpolarizing direction
• the unidirectional component is polarity is in the elongation direction at each voltage tested whereas in wild-type mice the polarity is in the contraction direction

nervous system
abnormal cochlear outer hair cell electromotility ( J:123299 )
• the voltage at highest gain is shifted from wild-type mice to nulls by 70.6 mV in the hyperpolarizing direction
• the unidirectional component is polarity is in the elongation direction at each voltage tested whereas in wild-type mice the polarity is in the contraction direction




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory