Phenotypes associated with this allele

• Allele Symbol: Pvr^tm1Gbn
• Allele Name: targeted mutation 1, Gunter Bernhardt
• Allele ID: MGI:3719436
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Pvr^tm1Gbn/Pvr^tm1Gbn	either: (involves: 129S2/SvPas) or (involves: 129S2/SvPas * BALB/c)	MGI:3720624

Genotype
MGI:3720624

hm1

• Allelic Composition: Pvr^tm1Gbn/Pvr^tm1Gbn
• Genetic Background: either: (involves: 129S2/SvPas) or (involves: 129S2/SvPas * BALB/c)

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

decreased IgA level ( J:123540 )

• following oral immunization with cholera toxin, IgA levels are decreased relative to wild-type mice

decreased IgG level ( J:123540 )

• following oral immunization with cholera toxin, IgG1, IgG2a and IgG2b levels are decreased relative to wild-type mice

decreased IgG1 level ( J:123540 )

decreased IgG2a level ( J:123540 )

decreased IgG2b level ( J:123540 )

abnormal response to infection ( J:123540 )

• following oral immunization with cholera toxin, IgA, IgG1, IgG2a and IgG2b levels are decreased relative to wild-type mice

hematopoietic system

decreased IgA level ( J:123540 )

• following oral immunization with cholera toxin, IgA levels are decreased relative to wild-type mice

decreased IgG level ( J:123540 )

• following oral immunization with cholera toxin, IgG1, IgG2a and IgG2b levels are decreased relative to wild-type mice

decreased IgG1 level ( J:123540 )

decreased IgG2a level ( J:123540 )

decreased IgG2b level ( J:123540 )