immune system
• bone marrow dendritic cells increases the production of IL-2 and interferon-gamma from transgenic DO11 T cells in vitro by 20% to 50% when compared to wild-type cells
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• in an in vitro assay with dendritic cell or an adoptive transfer experiment into mice, DO11 transgenic T cells are modestly stimulated to over-produce interferon-gamma
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• in an in vitro assay with dendritic cell or an adoptive transfer experiment into mice, DO11 transgenic T cells are modestly stimulated to over-produce IL-2
• in an adoptive transfer experiment into mice, IL-4+ DO11 transgenic cells are reduced by 60%
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