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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ophn1Wtgr
wavy tiger
MGI:3720821
Summary 4 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
ht1
 		Ophn1Wtgr/Ophn1+ D2(B6)-Ophn1Wtgr/EiGrsrJ MGI:3843832
ot2
 		Ophn1Wtgr/Y D2(B6)-Ophn1Wtgr/EiGrsrJ MGI:3843955
ot3
 		Ophn1Wtgr/Y involves: C57BL/6J * CAST/EiJ MGI:3844465
ot4
 		Ophn1Wtgr/Y involves: C57BL/6J * DBA/2J MGI:3844464


Genotype
MGI:3843832
ht1
Allelic
Composition		 Ophn1Wtgr/Ophn1+
Genetic
Background		 D2(B6)-Ophn1Wtgr/EiGrsrJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ophn1Wtgr mutation (1 available); any Ophn1 mutation (12 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
growth/size/body
decreased body size ( J:123336 )

reproductive system

pigmentation

integument
waved hair ( J:123336 )
• wavy coat appears striped
abnormal zigzag hair morphology ( J:123336 )
• zigzag hairs are abnormally thin, slightly wavy, and have clumps of melanin




Genotype
MGI:3843955
ot2
Allelic
Composition		 Ophn1Wtgr/Y
Genetic
Background		 D2(B6)-Ophn1Wtgr/EiGrsrJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ophn1Wtgr mutation (1 available); any Ophn1 mutation (12 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
preweaning lethality, incomplete penetrance ( J:123336 )
• Background Sensitivity: on the DBA/2J background very few hemizygotes occur, but they are found in significant numbers when outcrossed once to either C57BL/6J or CAST/EiJ

reproductive system
asthenozoospermia ( J:123336 )
• lack of mobility of most sperm with occassional motility for short periods of time

cellular
asthenozoospermia ( J:123336 )
• lack of mobility of most sperm with occassional motility for short periods of time




Genotype
MGI:3844465
ot3
Allelic
Composition		 Ophn1Wtgr/Y
Genetic
Background		 involves: C57BL/6J * CAST/EiJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ophn1Wtgr mutation (1 available); any Ophn1 mutation (12 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
mortality/aging ( J:123336 )
N
• Background Sensitivity: on the DBA/2J background very few hemizygotes occur, but they are found in significant numbers when outcrossed once to either C57BL/6J or CAST/EiJ




Genotype
MGI:3844464
ot4
Allelic
Composition		 Ophn1Wtgr/Y
Genetic
Background		 involves: C57BL/6J * DBA/2J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ophn1Wtgr mutation (1 available); any Ophn1 mutation (12 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
mortality/aging ( J:123336 )
N
• Background Sensitivity: on the DBA/2J background very few hemizygotes occur, but they are found in significant numbers when outcrossed once to either C57BL/6J or CAST/EiJ




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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory