About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tg(CYP1A1,CYP1A2)1Dwn
transgene insertion 1, Daniel W Nebert
MGI:3721236
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cx1
Cyp1atm1Dwn/Cyp1atm1Dwn
Tg(CYP1A1,CYP1A2)1Dwn/Tg(CYP1A1,CYP1A2)1Dwn
B6.Cg-Cyp1atm1Dwn Tg(CYP1A1,CYP1A2)1Dwn MGI:3721555


Genotype
MGI:3721555
cx1
Allelic
Composition
Cyp1atm1Dwn/Cyp1atm1Dwn
Tg(CYP1A1,CYP1A2)1Dwn/Tg(CYP1A1,CYP1A2)1Dwn
Genetic
Background
B6.Cg-Cyp1atm1Dwn Tg(CYP1A1,CYP1A2)1Dwn
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cyp1atm1Dwn mutation (0 available); any Cyp1a mutation (0 available)
Tg(CYP1A1,CYP1A2)1Dwn mutation (2 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
liver/biliary system
• after oral treatment with 125 mg/kg/day of benzo[a]pyrene BaP, mice show increased liver size

growth/size/body
• after oral treatment with 125 mg/kg/day of benzo[a]pyrene BaP, mice show increased liver size





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
11/12/2024
MGI 6.24
The Jackson Laboratory