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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Helttm1Yono
targeted mutation 1, Yuichi Ono
MGI:3721409
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Helttm1Yono/Helttm1Yono involves: 129S/SvEv * C57BL/6 MGI:3721940


Genotype
MGI:3721940
hm1
Allelic
Composition		 Helttm1Yono/Helttm1Yono
Genetic
Background		 involves: 129S/SvEv * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Helttm1Yono mutation (0 available); any Helt mutation (9 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
loss of GABAergic neurons ( J:124115 )
• at E12.5 and E13.5, GABAnergic neurons (Gad1+) are absent
abnormal glutaminergic neuron morphology ( J:124115 )
• at E12.5, glutamatergic neurons (Slc17a6+) are expanded




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory