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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Nmur1tm1Rtor
targeted mutation 1, Richard Torres
MGI:3722111
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Nmur1tm1Rtor/Nmur1tm1Rtor involves: 129S6/SvEvTac * C57BL/6NCr * C57BL/6NTac MGI:3722689
cx2
 		Nmur1tm1Rtor/Nmur1tm1Rtor
Nmur2tm1Rtor/Nmur2tm1Rtor 		involves: 129S1/Sv * 129S6/SvEvTac * C57BL/6NCr * C57BL/6NTac MGI:3722690


Genotype
MGI:3722689
hm1
Allelic
Composition		 Nmur1tm1Rtor/Nmur1tm1Rtor
Genetic
Background		 involves: 129S6/SvEvTac * C57BL/6NCr * C57BL/6NTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nmur1tm1Rtor mutation (0 available); any Nmur1 mutation (22 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
behavior/neurological phenotype ( J:124469 )
N
• mice have a normal response to chemical and thermal pain exposure




Genotype
MGI:3722690
cx2
Allelic
Composition		 Nmur1tm1Rtor/Nmur1tm1Rtor
Nmur2tm1Rtor/Nmur2tm1Rtor
Genetic
Background		 involves: 129S1/Sv * 129S6/SvEvTac * C57BL/6NCr * C57BL/6NTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nmur1tm1Rtor mutation (0 available); any Nmur1 mutation (22 available)
Nmur2tm1Rtor mutation (0 available); any Nmur2 mutation (28 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
increased thermal nociceptive threshold ( J:124469 )
• latency to respond to the hot plate test is increased relative to in wild-type mice but similar to in Nmur2tm1Rtor homozygotes




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory