All Phenotypes Vmn2r81<tm2Mom> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Vmn2r81^tm2Mom
targeted mutation 2, Peter Mombaerts
MGI:3722385

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Vmn2r81^tm2Mom/Vmn2r81^tm2Mom	B6;129P2-Vmn2r81^tm2Mom/MomJ	MGI:4850117
cx2	Del(17)5Mom/Del(17)5Mom Vmn2r81^tm2Mom/Vmn2r81^tm2Mom	involves: 129P2/OlaHsd * 129S6/SvEvTac * 129S7/SvEvBrd	MGI:5564785

Allelic Composition	Vmn2r81^tm2Mom/Vmn2r81^tm2Mom
Genetic Background	B6;129P2-Vmn2r81^tm2Mom/MomJ

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Vmn2r81^tm2Mom mutation (1 available); any Vmn2r81 mutation (54 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

normal phenotype

no abnormal phenotype detected ( J:166884 )

Allelic Composition	Del(17)5Mom/Del(17)5Mom Vmn2r81^tm2Mom/Vmn2r81^tm2Mom
Genetic Background	involves: 129P2/OlaHsd * 129S6/SvEvTac * 129S7/SvEvBrd

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Del(17)5Mom mutation (2 available); any Del(17)5Mom mutation (2 available)
Vmn2r81^tm2Mom mutation (1 available); any Vmn2r81 mutation (54 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

nervous system phenotype ( J:207447 )

N	• normal presynaptic terminal around vomeronasal sensory neuron glomeruli

abnormal vomeronasal sensory neuron morphology ( J:207447 )

• smaller glomeruli

abnormal vomeronasal sensory neuron physiology ( J:207447 )

• higher concentrations of VMR2R81 specific MHC peptides are required to induce calcium responses; however, maximum response remains the same

respiratory system

abnormal vomeronasal sensory neuron morphology ( J:207447 )

• smaller glomeruli

craniofacial

abnormal vomeronasal sensory neuron morphology ( J:207447 )

• smaller glomeruli

growth/size/body

abnormal vomeronasal sensory neuron morphology ( J:207447 )

• smaller glomeruli

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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