About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(Igk-Eik-H2-Ead)1Flv
transgene insertion 1, Richard A Flavell
MGI:3722860
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Tg(Igk-Eik-H2-Ead)1Flv/0
Tg(Tcra1H3.1,Tcrb1H3.1)1Vire/0 		involves: C57BL/6 * SJL MGI:3723061


Genotype
MGI:3723061
cx1
Allelic
Composition		 Tg(Igk-Eik-H2-Ead)1Flv/0
Tg(Tcra1H3.1,Tcrb1H3.1)1Vire/0
Genetic
Background		 involves: C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(Igk-Eik-H2-Ead)1Flv mutation (0 available)
Tg(Tcra1H3.1,Tcrb1H3.1)1Vire mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
thymus hypoplasia ( J:124574 )
• mice have drastic reduction in thymic cellularity
decreased double-positive T cell number ( J:124574 )
• significantly decreased numbers of CD4+CD8+ thymocytes

immune system
thymus hypoplasia ( J:124574 )
• mice have drastic reduction in thymic cellularity
decreased double-positive T cell number ( J:124574 )
• significantly decreased numbers of CD4+CD8+ thymocytes

endocrine/exocrine glands
thymus hypoplasia ( J:124574 )
• mice have drastic reduction in thymic cellularity




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory