Phenotypes associated with this allele

• Allele Symbol: Ackr3^tm1Fma
• Allele Name: targeted mutation 1, Fabienne Mackay
• Allele ID: MGI:3722943
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Ackr3^tm1Fma/Ackr3^tm1Fma Tg(Tek-cre)12Flv/?	involves: C3H * C57BL/6	MGI:3723119

Genotype
MGI:3723119

cn1

• Allelic Composition: Ackr3^tm1Fma/Ackr3^tm1Fma; Tg(Tek-cre)12Flv/?
• Genetic Background: involves: C3H * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

abnormal aortic valve cusp morphology ( J:124878 )

• 25% of neonates exhibit aortic valve tricuspids with thick leaflets

• 4.2% of neonates exhibit aortic valve bicuspids with thick leaflets

• 8.3% of neonates have an aortic valve bicuspid or unicuspid with an overgrown and obstructed leaflet

bicuspid aortic valve ( J:124878 )

• 4.2% of neonates exhibit aortic valve bicuspids with thick leaflets

• 8.3% of neonates have an aortic valve bicuspid or unicuspid with an overgrown and obstructed leaflet

thick aortic valve cusps ( J:124878 )

• 25% of neonates exhibit aortic valve tricuspids with thick leaflets

• 4.2% of neonates exhibit aortic valve bicuspids with thick leaflets

unicuspid aortic valve ( J:124878 )

• some neonates have an aortic valve unicuspid with an overgrown and obstructed leaflet

abnormal pulmonary valve cusp morphology ( J:124878 )

• 17% of neonates exhibit pulmonary valve tricuspids with thick leaflets

• 4.2% of neonates have a pulmonary valve bicuspid or unicuspid with an overgrown and obstructed leaflet

bicuspid pulmonary valve ( J:124878 )

• 4.2% of neonates have a pulmonary valve bicuspid or unicuspid with an overgrown and obstructed leaflet

thick pulmonary valve cusps ( J:124878 )

• 17% of neonates exhibit pulmonary valve tricuspids with thick leaflets

unicuspid pulmonary valve ( J:124878 )

• some neonates have a pulmonary valve unicuspid with an overgrown and obstructed leaflet

dilated heart right ventricle ( J:124878 )

• 26% of neonates have dilated right ventricles