All Phenotypes Foxp2<tm1.2Sfis> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Foxp2^tm1.2Sfis
targeted mutation 1.2, Simon E Fisher
MGI:3723630

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Foxp2^tm1Sfis/Foxp2^tm1.2Sfis Edil3^{Tg(Sox2-cre)1Amc}/?	involves: C57BL/6 * CBA * SJL	MGI:3723632

Allelic Composition	Foxp2^tm1Sfis/Foxp2^tm1.2Sfis Edil3^{Tg(Sox2-cre)1Amc}/?
Genetic Background	involves: C57BL/6 * CBA * SJL

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Edil3^{Tg(Sox2-cre)1Amc} mutation (5 available); any Edil3 mutation (43 available)
Foxp2^tm1.2Sfis mutation (0 available); any Foxp2 mutation (52 available)
Foxp2^tm1Sfis mutation (0 available); any Foxp2 mutation (52 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

lethality at weaning, complete penetrance ( J:125023 )

• mice die around P21

behavior/neurological

impaired righting response ( J:125023 )

nervous system

reduced cerebellar foliation ( J:125023 )

• cerebellum foliation is reduced

small cerebellum ( J:125023 )

vision/eye

delayed eyelid opening ( J:125023 )

• mice exhibit delayed eye opening compared to wild-type mice

growth/size/body

decreased body weight ( J:125023 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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