Phenotypes associated with this allele

• Allele Symbol: Plpp3^tm3.1Stw
• Allele Name: targeted mutation 3.1, Colin L Stewart
• Allele ID: MGI:3723634
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Plpp3^tm3.1Stw/Plpp3^tm3.1Stw	involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	MGI:3723636

Genotype
MGI:3723636

hm1

• Allelic Composition: Plpp3^tm3.1Stw/Plpp3^tm3.1Stw
• Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

prenatal lethality, complete penetrance ( J:125025 )

• no mice are recovered at birth

embryo

abnormal vitelline vasculature morphology ( J:125025 )

• at E9.5, yolk sac vasculature is poorly developed

abnormal embryo turning ( J:125025 )

• at E9.5, mice have not turned

embryonic growth retardation ( J:125025 )

• at E9.5, embryonic growth is delayed by 12 to 24 hours

abnormal neural fold morphology ( J:125025 )

• at E9.5, neural folds are misshapen and there is a kink in the neural tube

kinked neural tube ( J:125025 )

• at E9.5

abnormal allantois morphology ( J:125025 )

• at E9.5, allantoises are hemorrhagic, enlarged and turned towards the embryo

enlarged allantois ( J:125025 )

• at E9.5

failure of chorioallantoic fusion ( J:125025 )

• at E9.5, no chorio-allantoic fusion is evident

nervous system

kinked neural tube ( J:125025 )

• at E9.5

growth/size/body

embryonic growth retardation ( J:125025 )

• at E9.5, embryonic growth is delayed by 12 to 24 hours

cardiovascular system

abnormal vitelline vasculature morphology ( J:125025 )

• at E9.5, yolk sac vasculature is poorly developed

hemorrhage ( J:125025 )

• at E9.5, allantoises are hemorrhagic