Phenotypes associated with this allele

• Allele Symbol: Plpp3^tm2Stw
• Allele Name: targeted mutation 2, Colin L Stewart
• Allele ID: MGI:3723646
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Plpp3^tm2Stw/Plpp3^tm2Stw	involves: 129S1/Sv * C57BL/6J	MGI:3826989

Genotype
MGI:3826989

hm1

• Allelic Composition: Plpp3^tm2Stw/Plpp3^tm2Stw
• Genetic Background: involves: 129S1/Sv * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

prenatal lethality ( J:142493 )

embryo

abnormal gastrulation ( J:142493 )

• low penetrance of gastrulation defects

embryonic growth retardation ( J:142493 )

• developmental delay of about 12 to 24 hours

open neural tube ( J:142493 )

• frequently seen in the best developed embryos

abnormal allantois morphology ( J:142493 )

• allantois compaction

failure of chorioallantoic fusion ( J:142493 )

• absence of fusion at the 6 somite stage

abnormal vitelline vascular remodeling ( J:142493 )

• impaired remodeling of the primary vascular plexus

nervous system

open neural tube ( J:142493 )

• frequently seen in the best developed embryos

growth/size/body

embryonic growth retardation ( J:142493 )

• developmental delay of about 12 to 24 hours