All Phenotypes Ophn1<tm2Bill> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Ophn1^tm2Bill
targeted mutation 2, Pierre Billuart
MGI:3757642

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Ophn1^tm2Bill/Y	Not Specified	MGI:3758488

Allelic Composition	Ophn1^tm2Bill/Y
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ophn1^tm2Bill mutation (1 available); any Ophn1 mutation (12 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

abnormal dendrite morphology ( J:124943 )

• when neurons are infected with an adenovirus cre recombinase and allowed to differentiate there is an increase in immature dendritic protrusions similar to that observed in Ophn1^tm1Bill male mice

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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