Phenotypes associated with this allele

• Allele Symbol: Reln^rl-7J
• Allele Name: reeler 7 Jackson
• Allele ID: MGI:3757710
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Reln^rl-7J/Reln^rl-7J	C57BL/6J-Reln^rl-7J/GrsrJ	MGI:3760404

Genotype
MGI:3760404

hm1

• Allelic Composition: Reln^rl-7J/Reln^rl-7J
• Genetic Background: C57BL/6J-Reln^rl-7J/GrsrJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

premature death ( J:125130 )

• homozygotes have not lived to adulthood

nervous system

abnormal hippocampus morphology ( J:125130 )

• neurons of the hippocamnpal gyrus are scattered in irregular wavy layers

abnormal cerebral cortex morphology ( J:125130 )

abnormal stratification in cerebral cortex ( J:125130 )

• scrambled layering in the cortex

abnormal cerebellar Purkinje cell layer ( J:125130 )

• the cerebellum is small with scrambled Purkinjie and granule cells

small cerebellum ( J:125130 )

behavior/neurological

ataxia ( J:125130 )

• by 2 weeks of age honozygotes lean side-to-side as they walk

impaired balance ( J:125130 )

• honozygotes are unable to keep their hindquarters upright and they frequently fall on their side

abnormal gait ( J:125130 )