neoplasm
• lymphomagenesis is enhanced in the few surviving mice relative to in Tg(SV40-NRAS*G12D)1Sco mice
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Allele Symbol Allele Name Allele ID |
Tg(SV40-NRAS*G12D)1Sco transgene insertion 1, Suzanne Cory MGI:3757990 |
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Summary |
3 genotypes
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♀ | phenotype observed in females |
♂ | phenotype observed in males |
N | normal phenotype |
• lymphomagenesis is enhanced in the few surviving mice relative to in Tg(SV40-NRAS*G12D)1Sco mice
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♀ | phenotype observed in females |
♂ | phenotype observed in males |
N | normal phenotype |
• lymphomagenesis is enhanced relative to in Tg(SV40-NRAS*G12D)1Sco mice
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♀ | phenotype observed in females |
♂ | phenotype observed in males |
N | normal phenotype |
• two female primary transgenic mice develop T cell lymphomas, one at 10 weeks and the other at 17
• during the first 6 months of life, 9 females and 3 males develop thymic T cell lymphomas while 10 females and 3 males develop thymic T cell lymphomas and reticulum cell sarcoma type A together
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• during the first 6 months of life, 10 females and 17 males develop reticulum cell sarcoma type A while 10 females and 3 males develop thymic T cell lymphomas and reticulum cell sarcoma type A together
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• two female primary transgenic mice develop T cell lymphomas, one at 10 weeks and the other at 17
• during the first 6 months of life, 9 females and 3 males develop thymic T cell lymphomas while 10 females and 3 males develop thymic T cell lymphomas and reticulum cell sarcoma type A together
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/21/2024 MGI 6.24 |
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